What's the most weird or interesting cultural footprint a piece of media has left?

This was after seeing that "Yu-Gi-Oh created the uwu" post. For me, it was that time when the Chainsaw Man portrayal of Denji barking at Makima created this social media phenomenon where a girl posted a suggestive photo/cosplay and guys would spam "BARK BARK BARK WOOF WOOF" in the comments. Such an odd time to be in twitter or instagram.